Osteoarthritis is a disease that can cause serious discomfort in the joints, which affects 15% of the World population and costs more than 4,900 million each year.
This article explains the pathogenesis of osteoarthritis and how mesenchymal stem cells may play a role in future treatment strategies of this disabling condition, and that stem cell transplantation can help reduce discomfort and pain or even eliminate Arthritis, in a permanent, safe and effective way.
First, we must take into account that arthritis is not a unique disease, but is the result of more than 100 diseases that cause joint problems or pains.
There are two types of arthritis, rheumatoid and osteoarthrosis, that affect people of any age and genetic background, and is one of the main causes of disability in the world. Although it is more common to affect women of more advanced age, it can also afflict men.
Usually, men and women between 40 and 65 years suffer some kind of problem related to the joints that can trigger in osteoarthritis, which can also affect hips, knees, spinal cord and joints in the fingers. Joint stiffness can degenerate into rheumatoid arthritis that easily causes deformities in the affected limbs.
All these ailments can now be treated with stem cells to recover and protect the integrity of the cartilage, which, naturally, is slowly wearing down to the point of generating mild discomfort or severe pain.
The economic and health impact of osteoarthritis has become an international public health priority and has led to the exploration and active investigation of alternative preservation and joint preservation therapies, including mesenchymal stem cells.
Osteoarthrosis is more common in advanced ages and can now be treated with stem cell treatments, as evidenced by independent research from different experts around the world.
Stem cell treatment can be effective for:
Stem cell transplantation is a good alternative for the treatment of osteoarthritis and invasive surgeries of hip or knee replacement.
Regenerative medicine offers the potential to develop alternatives to total joint replacement for the treatment of osteoarthritis.
Stem cells are the building blocks of all human tissues. Stem cells have potential as a treatment, in part, because they can communicate valuable information about tissue growth and healing to other cells in the body.
Stem cell treatments have shown their efficacy in the treatment of other previously intractable diseases such as Alzheimer’s, paralysis due to injuries, cerebral palsy, spinal injuries, ataxia and liver diseases, more info here.
A growing interest in the area of regenerative medicine, led by a better understanding of the role of mesenchymal stem cells (MSCs) in homeostasis and tissue repair, has seen recent efforts to explore the potential of stem cell therapies in the Active treatment of symptomatic osteoarthritis.
It is encouraging that the results of clinical and preclinical trials have provided initial evidence on the efficacy and safety needed in the therapeutic use of mesenchymal stem cell therapies for the treatment of osteoarthritis.