In a paper published in the journal Molecular Cell on Thursday, Scaffidi and his colleagues from Francis Crick Institute, have discovered a set of simple rules that determine the precision of CRISPR/Cas9 genome editing in humans. They believe this will help to improve the efficiency and safety of genome editing in both the lab and the clinic.
A system formerly thought to be near-impenetrable, CRISPR has been developed with the hope of targeting DNA to overcome a plethora of biological ailments. Among other things, the successful implementation of CRISPR means scientists could cure HIV or Alzheimer’s disease.
The CRISPR-Cas9 system has generated a lot of excitement in the scientific community because it is faster, cheaper, more accurate, and more efficient than other existing methods of genome editing in humans.
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